Structure of PDB 8d1v Chain A Binding Site BS02

Receptor Information
>8d1v Chain A (length=1229) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNT
KGRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQ
LRQRSTLRWTDKNPCPDNAETYCPFCELLGRSGKDWRFRIHFGNLSLPGK
PDFDGPKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDN
KVSAEARKLLCDSLKFTDRLCGALCVIRFDPNANLAEKTAEQIISILDDN
KKTEYTRLLADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGKKKKDENS
VTIRQILTTSADTKELKNAGKWREFCEKLGEALYLKSKDMFHGKPDRLEK
SRSVSIGSVLKETVVCGELVAKTPFFFGAIDEDAKQTDLQVLLTPDNKYR
LPRSAVRGILRRDLQTYFDSPCNAELGGRPCMCKTCRIMRGITVMDARSE
YNAPPEIRHRTRINPFTGTVAEGALFNMEVAPEGIVFPFQLRYRGSEDGL
PDALKTVLKWWAEGQAFMSGAASTGKGRFRMENAKYETLDLSDENQRNDY
LKNWGWRDEKGLEELKKRLNSGLPEPGNYRDPKWHEINVSIEMASPFING
DPIRAAVDKRGTDVVTFVKYKAEGEEAKPVCAYKAESFRGVIRSAVARIH
MEDGVPLTELTHSDCECLLCQIFGSEYEAGKIRFEDLVFESDPEPVTFDH
VAIDRFTGGAADKKKFDDSPLPGSPARPLMLKGSFWIRRDVLEDEEYCKA
LGKALADVNNGLYPLGGKSAIGYGQVKSLGIKGDDKRISRLMNPAFDETD
VAVPEKPKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQKFHEGRL
TGKIRCKLITKTPLIVPDTSNDDFFRPADKEARKEKDEYHKSYAFFRLHK
QIMIPGSELRGMVSSVYETVTNSCFRIFDETKRLSWRVDDRMIGKRMSAD
LRPCHGDEKRLLLRHPKGLCPACRLFGTGSYKGRVRFGFASLENDPEWLI
PGKNPGDPFHGGPVMLSLLERPRPTWSIPGSDNKFKVPGRKFYVHHHAWK
TIKDGNHPTTGKAIEQSPNNRTVEALAGGNSFSFEIAFENLKEWELGLLI
HSLQLEKGLAHKLGMAKSMGFGSVEIDVESVRLRKDWKQWRNGNSEIPNW
LGKGFAKLKEWFRDELDFIENLKKLLWFPEGDQAPRVCYPMLRKKDDPNG
NSGYEELKDGEFKKEDRQKKLTTPWTPWA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d1v Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA.
Resolution2.82 Å
Binding residue
(original residue number in PDB)
Y281 R283 H306 Y313 D429 R503 A512 E513 G514 L516 F517 D654 D753 K754 K755 K756 F757 L1391 E1392 R1393 N1441 R1443 L1564 R1565
Binding residue
(residue number reindexed from 1)
Y255 R257 H280 Y287 D388 R462 A471 E472 G473 L475 F476 D613 D712 K713 K714 K715 F716 L1019 E1020 R1021 N1069 R1071 L1192 R1193
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:8d1v, PDBe:8d1v, PDBj:8d1v
PDBsum8d1v
PubMed36190192
UniProtA0A401FT36

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