Structure of PDB 8cj2 Chain A Binding Site BS02
Receptor Information
>8cj2 Chain A (length=154) Species:
9606
(Homo sapiens) [
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MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAES
EEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCT
YRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFH
INWE
Ligand information
>8cj2 Chain F (length=8) Species:
9606
(Homo sapiens) [
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EKIARARI
Receptor-Ligand Complex Structure
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PDB
8cj2
Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Resolution
2.127 Å
Binding residue
(original residue number in PDB)
V6 N7 V9 S142 P144 R145 V146 R148
Binding residue
(residue number reindexed from 1)
V6 N7 V9 S142 P144 R145 V146 R148
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006325
chromatin organization
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:8cj2
,
PDBe:8cj2
,
PDBj:8cj2
PDBsum
8cj2
PubMed
37347155
UniProt
Q9Y294
|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)
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