Structure of PDB 8cis Chain A Binding Site BS02

Receptor Information
>8cis Chain A (length=312) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQD
TKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRL
FFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDK
LLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMY
GVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFN
DKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE
VQQMKAQAREEK
Ligand information
>8cis Chain C (length=14) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GGSSWEYIWTLPSG
Receptor-Ligand Complex Structure
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PDB8cis The FERM domain of human moesin with two bound peptides identified by phage display
Resolution1.52 Å
Binding residue
(original residue number in PDB)		W242 N247 I248 F250 N251 D252 L274 K278 L281 H288
Binding residue
(residue number reindexed from 1)		W241 N246 I247 F249 N250 D251 L273 K277 L280 H287
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Cellular Component
GO:0005856 cytoskeleton

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Molecular Function
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Cellular Component
External links
PDB RCSB:8cis, PDBe:8cis, PDBj:8cis
PDBsum8cis
PubMed37866628
UniProtP26038|MOES_HUMAN Moesin (Gene Name=MSN)

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