Structure of PDB 8cip Chain A Binding Site BS02

Receptor Information
>8cip Chain A (length=665) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIEELAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKFMNHNPAN
PNWFNRDRFVLSAGHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHP
EYGHTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFEIINHYTYA
ICGDGDLMEGVASEAASLAGHLKLGRLIVLYDSNDISLDGELNLSFSENV
AQRFQAYGWQYLRVEDGNNIEEIAKALEEARADLSRPTLIEVKTTIGYGA
PNKAGTSGVHGAPLGAQEAKLTKEAYRWTFAEDFYVPEEVYAHFRATVQE
PGAKKEAKWNEQLAAYEQAHPELAAQLKRAIEGKLPDGWEASLPVYEAGK
SLATRSSSGEVINAIAKAVPQLFGGSADLASSNKTLIKGGGNFFPGSYEG
RNVWFGVREFAMGAALNGMALHGGLKVFGGTFFVFSDYLRPAIRLAALMG
LPVIYVLTHDSIAVGEDGPTHEPIEQLASLRAMPNLSVIRPADANETAAA
WRLALESTDKPTALVLTRQDVPTLAATAELAYEGVKKGAYVVSPAKNGAP
EALLLATGSEVGLAVKAQEALAAEGIHVSVISMPSWDRFEAQPKSYRDEV
LPPAVTKRLAIEMGASLGWERYVGAEGDILAIDRFGASAPGEKIMAEYGF
TVDNVVRRTKALLGK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8cip Chain A Residue 810 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cip Thermostable Transketolase from Geobacillus stearothermophilus: Characterization and Catalytic Properties
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D157 N187 I189
Binding residue
(residue number reindexed from 1)		D154 N184 I186
Annotation score1
Enzymatic activity
Enzyme Commision number 2.2.1.1: transketolase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004802 transketolase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006098 pentose-phosphate shunt
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8cip, PDBe:8cip, PDBj:8cip
PDBsum8cip
PubMed
UniProtA0A0I9QGZ2|TKT_GEOSE Transketolase (Gene Name=tkt)

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