Structure of PDB 8bx1 Chain A Binding Site BS02

Receptor Information
>8bx1 Chain A (length=127) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMDMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTI
SRFEALQLSLKNMSKLRPLLEKWVEEADNNRVRWSLETMFLKSPKPSLQQ
ITHIANQLGLEKDVVRVWFSNRRQKGK
Ligand information
Receptor-Ligand Complex Structure
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PDB8bx1 Crystal structure of Oct4-Soc2-HoxB1 complex
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R20 T26 Q27 Q44 S48 V139 N143
Binding residue
(residue number reindexed from 1)		R23 T29 Q30 Q47 S51 V117 N121
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8bx1, PDBe:8bx1, PDBj:8bx1
PDBsum8bx1
PubMed
UniProtP20263|PO5F1_MOUSE POU domain, class 5, transcription factor 1 (Gene Name=Pou5f1)

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