Structure of PDB 8bvl Chain A Binding Site BS02

Receptor Information
>8bvl Chain A (length=145) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQ
EDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRC
TVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8bvl Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8bvl Structural basis for ubiquitylation by HOIL-1.
Resolution2.24 Å
Binding residue
(original residue number in PDB)		C447 C450 C465 C468
Binding residue
(residue number reindexed from 1)		C82 C85 C100 C103
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.31: RBR-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:8bvl, PDBe:8bvl, PDBj:8bvl
PDBsum8bvl
PubMed36685275
UniProtQ9BYM8|HOIL1_HUMAN RanBP-type and C3HC4-type zinc finger-containing protein 1 (Gene Name=RBCK1)

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