Structure of PDB 8bn2 Chain A Binding Site BS02

Receptor Information
>8bn2 Chain A (length=266) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIY
QAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKR
YMDYSVGILIKKGTPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPL
EQDSTFAELWRTISKNGGADNCVSSPSEGIRKAKKGNYAFLWDVAVVEYA
ALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDV
LKQKWWPHMGRCDLTS
Ligand information
Ligand IDDSN
InChIInChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
InChIKeyMTCFGRXMJLQNBG-UWTATZPHSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](CO)C(O)=O
OpenEye OEToolkits 1.5.0C([C@H](C(=O)O)N)O
CACTVS 3.341N[C@H](CO)C(O)=O
OpenEye OEToolkits 1.5.0C(C(C(=O)O)N)O
ACDLabs 10.04O=C(O)C(N)CO
FormulaC3 H7 N O3
NameD-SERINE
ChEMBLCHEMBL285123
DrugBankDB03929
ZINCZINC000000895342
PDB chain8bn2 Chain A Residue 907 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8bn2 Crystal structure of the ligand-binding domain (LBD) of human iGluR Delta-1 (GluD1) in complex with D-Serine
Resolution1.63 Å
Binding residue
(original residue number in PDB)		Y492 A519 T521 R526 Y539 W741 D742
Binding residue
(residue number reindexed from 1)		Y57 A84 T86 R91 Y104 W192 D193
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8bn2, PDBe:8bn2, PDBj:8bn2
PDBsum8bn2
PubMed38060673
UniProtQ9ULK0|GRID1_HUMAN Glutamate receptor ionotropic, delta-1 (Gene Name=GRID1)

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