Structure of PDB 8att Chain A Binding Site BS02

Receptor Information
>8att Chain A (length=906) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALNIFNQDRQKVLENRATEAARERWKHDFEEAKARGDISIEKNLNVKLWK
WYNEMLPLVKEEINHCRSLLSEKLSDKKGLNKVDTNRLGYGPYLTLIDPG
KMCVITILELLKLNSTGGVIEGMRTARAVISVGKAIEMEFRSEQVLKSES
QAKILWPQSIRARIGSVLISMLIQVAKVSVQGVDPVTKAKVHGEAPAFAH
GYQYHNGSKLGVLKIHKTLIRQLNGERLIASVQPQLLPMLVEPKPWVNWR
SGGYHYTQSTLLRTKDSPEQVAYLKAASDNGDIDRVYDGLNVLGRTPWTV
NRKVFDVVSQVWNKGEGFLDIPGAQDEMVLPPAPPKNSDPSILRAWKLQV
KTIANKFSSDRSNRCDTNYKLEIARAFLGEKLYFPHNLDFRGRAYPLSPH
FNHLGNDMSRGLLIFWHGKKLGPSGLKWLKIHLSNLFGFDKLPLKDRVAF
TESHLQDIKDSAENPLTGDRWWTTADKPWQALATCFELNEVMKMDNPEEF
ISHQPVHQDGTCNGLQHYAALGGDVEGATQVNLVPSDKPQDVYAHVARLV
QKRLEIAAEKGDENAKILKDKITRKVVKQTVMTNVYGVTYVGATFQIAKQ
LSPIFDDRKESLDFSKYLTKHVFSAIRELFHSAHLIQDWLGESAKRISKS
IRLDVDEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYREESKKQVETNLQT
VFISDPFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFAS
VHDSYWTHASDIDTMNVVLREQFIKLHEVDLVLRLKEEFDQRYKNYVKIG
KLKRSTDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNSPLIED
RNVGEKMVTTVSLFEDITDLDALEGMSVLLPLRLPEIPPKGDFDVTVLRN
SQYFFS
Ligand information
Receptor-Ligand Complex Structure
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PDB8att Structures illustrate step-by-step mitochondrial transcription initiation
Resolution3.44 Å
Binding residue
(original residue number in PDB)		R530 R533 Y638 S644 K645 G647 R699 R827 T1019 G1023 V1024 T1025 V1027 Y1122 Q1129 Q1135 F1138 R1151 R1152
Binding residue
(residue number reindexed from 1)		R124 R127 Y202 S208 K209 G211 R263 R391 T583 G587 V588 T589 V591 Y686 Q693 Q699 F702 R715 R716
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001018 mitochondrial promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003896 DNA primase activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0000002 mitochondrial genome maintenance
GO:0006269 DNA replication, synthesis of primer
GO:0006351 DNA-templated transcription
GO:0006390 mitochondrial transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0034245 mitochondrial DNA-directed RNA polymerase complex
GO:0042645 mitochondrial nucleoid
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8att, PDBe:8att, PDBj:8att
PDBsum8att
PubMed37821701
UniProtP13433|RPOM_YEAST DNA-directed RNA polymerase, mitochondrial (Gene Name=RPO41)

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