Structure of PDB 7zx4 Chain A Binding Site BS02

Receptor Information
>7zx4 Chain A (length=360) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIID
MNDPSNPIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTM
TDDVTFWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQII
NYRTDAKQKWLLLTGISAQQNRVVGAMQLYSVDRKVSQPIEGHAASFAQF
KMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGNQPFPKKAVDVFFPP
EAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISGETIF
VTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVR
NNLAGAEELF
Ligand information
Receptor-Ligand Complex Structure
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PDB7zx4 Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Resolution2.08 Å
Binding residue
(original residue number in PDB)
N117 E133 A160
Binding residue
(residue number reindexed from 1)
N113 E129 A156
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030130 clathrin coat of trans-Golgi network vesicle
GO:0030132 clathrin coat of coated pit

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7zx4, PDBe:7zx4, PDBj:7zx4
PDBsum7zx4
PubMed37219487
UniProtQ00610|CLH1_HUMAN Clathrin heavy chain 1 (Gene Name=CLTC)

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