Structure of PDB 7zpp Chain A Binding Site BS02

Receptor Information
>7zpp Chain A (length=275) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKMPST
LRGSNKRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRV
QTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQA
LVERTHQTLKNTLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIF
IFNKEQQRIQQQSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAI
VVKDRGTDRYLVIANKDVKFIPPPK
Ligand information
Receptor-Ligand Complex Structure
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PDB7zpp A supramolecular assembly mediates lentiviral DNA integration
Resolution4.5 Å
Binding residue
(original residue number in PDB)		R53 G54 S55 I143 Q148 A151 R155
Binding residue
(residue number reindexed from 1)		R52 G53 S54 I142 Q147 A150 R154
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7zpp, PDBe:7zpp, PDBj:7zpp
PDBsum7zpp
PubMed28059770
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

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