Structure of PDB 7zlu Chain A Binding Site BS02

Receptor Information
>7zlu Chain A (length=278) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHAEINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLSPSFKD
FIPHMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPLSL
DKVIFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYRFWKTG
YWANYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPNSLANL
DQDLPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNPMTKEP
KLDRARRQVPEWTKYDEEIAELARRVRE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7zlu Chain A Residue 1503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zlu A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein quality control checkpoint
Resolution2.049 Å
Binding residue
(original residue number in PDB)		D1302 D1304 D1435
Binding residue
(residue number reindexed from 1)		D107 D109 D240
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7zlu, PDBe:7zlu, PDBj:7zlu
PDBsum7zlu
PubMed37822503
UniProtG0SB58

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