Structure of PDB 7ziu Chain A Binding Site BS02

Receptor Information
>7ziu Chain A (length=603) Species: 64292 (Ntaya virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNWKMVEDRVKKLADEFSTTWHYDSEHPYKTWNYHGSYEVKATGSASSMV
NGVVRVLSKPWDTLAMTDTTPFGQQRVFKEKVDTKAPEPPKGTAEVMRVT
AKWMWKFVGRSKTPRVCTKEEFIAKVNSHQNRWASAREAVEDPAFWEMVD
REREAHLQGRCEMCTYNMMGKREKKMGEFGKAKGSRAIWYMWLGSRYLEF
EALGFLNEDHWMSRENTLGGVEGLGLQKLGYVLRDIAKNPGGLMYADDTA
GWDTRITKADLENESIVLEMMTPEHRALAEPLIKFAYMNKVVKVMRPGAD
GITVMDVISREDQRGSGQVVTYALNTFTNLCVQLIRCMEGEGLLKPEEVE
KLERGKQRKIQDWLDKNGTERLASMAVSGDDCVVKPKDDRFATALHFLNS
MSKIRKDIPEWKQSTGWRNWQDVPFCSHHFHELTMKDGRQIVVPCRHQDE
LIGRARLSPGSGWSLTETACLSKAYGQMWLLMYFHRRDLRLMANAICSAV
PVSWVPTGRTTWSIHGKGEWMTTEDMLRVWNRVWIEENEHMEDKTPVSSW
NDVPYLGKREDSWCGSLIGHRARSTWAENIYTPIMQIRGLIGPERYVDYM
PTL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7ziu Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ziu Crystal structure of Ntaya virus NS5 polymerase domain
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H717 H719 C733 C852
Binding residue
(residue number reindexed from 1)		H429 H431 C445 C564
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity
GO:0005524 ATP binding
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7ziu, PDBe:7ziu, PDBj:7ziu
PDBsum7ziu
PubMed38781970
UniProtK0BRZ6

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