Structure of PDB 7yx8 Chain A Binding Site BS02

Receptor Information
>7yx8 Chain A (length=440) Species: 239935 (Akkermansia muciniphila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGGGPDYLYAEYRALPSPRQTGKNLRIGDGFSKYDNMTGVYLEKGRHVVL
VGKTEGQEISLLLPNLMRKPAEGVQPTKDPNGWGLHKKQIPLKEGINIID
VETPANAYISYFTEDAGKAPKIPVHFVTGKANGYFDTTRGDTNKDWVRLL
DQAVSPIMDARGKYIQVAYPVEFLKKFTKDRGTELINAYDKLIGIQYQLM
GLDKYGKIPENRVLARVNFNYYMFRDGDGVAYLGNDGTMRMVTDPENVLK
GDACWGFSHAVGHVMQMRPMTWGGMTEVSNNIFSLQAAAKTGNESRLKRQ
GSYDKARKEIIEGEIAYLQSKDVFNKLVPLWQLHLYFTKNGHPDFYPDVM
EYLRNNAGNYGGNDTVKYQFEFVKACCDVTKTDLTDFFEKWGFFKPGKFH
IGDYAQYDFNVTPEMVEETKKWIAGKGYPKPETDITELSE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yx8 Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		Y287 Y288 F290 R291 D292 G293 H325 H329 Y470
Binding residue
(residue number reindexed from 1)		Y221 Y222 F224 R225 D226 G227 H259 H263 Y404
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7yx8, PDBe:7yx8, PDBj:7yx8
PDBsum7yx8
PubMed35882872
UniProtB2UPI7

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