Structure of PDB 7yna Chain A Binding Site BS02

Receptor Information
>7yna Chain A (length=1536) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNT
KGRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQ
LRQRSTLRWTDKNPCPDNAETYCPFCELLGRRFRIHFGNLSLPGKPDFDG
PKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDNKVSAE
ARKLLCDSLKFTDRLCGALCVIRFDNLAEKTAEQIISILDDNKKTEYTRL
LADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGKKKKDENSVTIRQILT
TSADTKELKNAGKWREFCEKLGEALYLKSKDMDAEFHGKPDRLEKSRSVS
IGSVLKETVVCGELVAKTPFFFGAIDEDAKQTDLQVLLTPDNKYRLPRSA
VRGILRRDLQTYFDSPCNAELGGRPCMCKTCRIMRGITVMDARSEYNAPP
EIRHRTRINPFTGTVAEGALFNMEVAPEGIVFPFQLRYRGSEDGLPDALK
TVLKWWAEGQAFMSGAASTGKGRFRMENAKYETLDLSDENQRNDYLKNWG
WRDEKGLEELKKRLNSGLPEPGNYRDPKWHEINVSIEMASPFINGDPIRA
AVDKRGTDVVTFVKYKAEGEEAKPVCAYKAESFRGVIRSAVARIHMEDGV
PLTELTHSDCECLLCQIFGSEYEAGKIRFEDLVFESDPEPVTFDHVAIDR
FTGGAADKKKFDDSPLPGSPARPLMLKGSFWIRRDVLEDEEYCKALGKAL
ADVNNGLYPLGGKSAIGYGQVKSLGIKGDDKRISRLMNPAFDETDVAVPE
KPKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQKFHEGRLTGKIR
CKLITKTPLIVPDTSNDDFFRPADKEARKEKDEYHKSYAFFRLHKQIMIP
GSELRGMVSSVYETVTNSCFRIFDETKRLSWRMDADHQNVLQDFLPGRVT
ADGKHIQKFSETARVPFYDKTQKHFDILDEQEIAGEKPVRMWVKRFIKRL
SLVDPAKHPQKKQDNKWKRRKEGIATFIEQKNGSYYFNVVTNNGCTSFHL
WHKPDNFDQEKLEGIQNGEKLDCWVRDSRYQKAFQEIPENDPDGWECKEG
YLHVVGPSKVEFSDKKGDVINNFQGTLPSVPNDWKTIRTNDFKNRKRKNE
PVFCCEDDKGNYYTMAKYCETFFFDLKENEEYEIPEKARIKYKELLRVYN
NNPQAVPESVFQSRVARENVEKLKSGDLVYFKHNEKYVEDIVPVRISRTV
DDRMIGKRMSADLRPCHGDWRHPKGLCPACRLFGTGSYKGRVRFGFASLE
NDPEWLIPGKNPGDPFHGGPVMLSLLERPRPTWSIPGSDNKFKVPGRKFY
VHHHAWKTIKDGNHPTTGKAIEQSPNNRTVEALAGGNSFSFEIAFENLKE
WELGLLIHSLQLEKGLAHKLGMAKSMGFGSVEIDVESVRLRKDWKQWRNG
NSEIPNWLGKGFAKLKEWFRDELDFIENLKKLLWFPEGDQAPRVCYPMLR
KKDDPNGNSGYEELKDGEFKKEDRQKKLTTPWTPWA
Ligand information
>7yna Chain C (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaguaacgauguuguucaaguuccu
.........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yna Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector.
Resolution3.64 Å
Binding residue
(original residue number in PDB)		R283 K364 D429 E513 G514 L516 E717 K754 K756 F757 A981 H983 R1041 R1125 E1157 S1159 Q1250 L1390 E1392 N1441 L1564 R1565
Binding residue
(residue number reindexed from 1)		R249 K330 D383 E467 G468 L470 E671 K708 K710 F711 A935 H937 R995 R1079 E1111 S1113 Q1204 L1325 E1327 N1376 L1499 R1500
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:7yna, PDBe:7yna, PDBj:7yna
PDBsum7yna
PubMed36702942
UniProtA0A401FT36

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