Structure of PDB 7yl0 Chain A Binding Site BS02

Receptor Information
>7yl0 Chain A (length=37) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Ligand information
>7yl0 Chain I (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TQRLANFLVHSSNNFGAILSSTNVGSNTY
Receptor-Ligand Complex Structure
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PDB7yl0 A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core
Resolution3.2 Å
Binding residue
(original residue number in PDB)
G33 N35 X37
Binding residue
(residue number reindexed from 1)
G33 N35 X37
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:7yl0, PDBe:7yl0, PDBj:7yl0
PDBsum7yl0
PubMed36567711
UniProtP10997|IAPP_HUMAN Islet amyloid polypeptide (Gene Name=IAPP)

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