Structure of PDB 7yh4 Chain A Binding Site BS02
Receptor Information
>7yh4 Chain A (length=400) Species:
9606
(Homo sapiens) [
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LYFQGSLELLKLRSAECIDEAAERLGALSRAIWSQPELAYEEHHAHRVLT
HFFEREPPAASWAVQPHYQLPTAFRAEWEPPEARPRPLHLGFLCEYDALP
GIGHACGHNLIAEVGAAAALGVRGALEGLPRPPPPVKVVVLGTPAEEDGG
GKIDLIEAGAFTNLDVVFMAHPSQENAAYLPDMAEHDVTVKYYGKASHSA
SYPWEGLNALDAAVLAYNNLSVFRQQMKPTWRVHGIIKNGGVKPNIIPSY
SELIYYFRAPSMKELQVLTKKAEDCFRAAALASGCTVEIKGGAHDYYNVL
PNKSLWKAYMENGRKLGIEFIGSTDFGNVSFVVPGIHPYFHIGSNALNHT
EQYTEAAGSQEAQFYTLRTAKALAMTALDVIFKPELLEGIREDFKLKLQE
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
7yh4 Chain A Residue 502 [
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Receptor-Ligand Complex Structure
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PDB
7yh4
Crystal structure of human cytosolic beta-alanyl lysine dipeptidase (PM20D2)
Resolution
2.03 Å
Binding residue
(original residue number in PDB)
H126 H189
Binding residue
(residue number reindexed from 1)
H108 H171
Annotation score
1
Enzymatic activity
Enzyme Commision number
3.4.13.4
: Xaa-Arg dipeptidase.
Gene Ontology
Molecular Function
GO:0004180
carboxypeptidase activity
GO:0005515
protein binding
GO:0016787
hydrolase activity
GO:0016805
dipeptidase activity
GO:0042802
identical protein binding
GO:0071713
para-aminobenzoyl-glutamate hydrolase activity
Biological Process
GO:0006508
proteolysis
GO:0046657
folic acid catabolic process
GO:0051246
regulation of protein metabolic process
Cellular Component
GO:0005654
nucleoplasm
GO:0005737
cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:7yh4
,
PDBe:7yh4
,
PDBj:7yh4
PDBsum
7yh4
PubMed
UniProt
Q8IYS1
|P20D2_HUMAN Xaa-Arg dipeptidase (Gene Name=PM20D2)
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