Structure of PDB 7yg6 Chain A Binding Site BS02

Receptor Information
>7yg6 Chain A (length=727) Species: 31330 (Ephydatia fluviatilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QRGSSGQPVPVSANYLPLKGNMDGVFKYAVGFNPPVEDIRSRSQLLNEHK
ELIGLTRVFDGSTLYVPKRICEQRLDLMSTRQTDGASIKVTISLVDSVKN
RDVVQLMNVIFKRILRSLKLQRIGRDYYDANSPLEVPQHKMQLWPGYVTA
INRHEGGLMLVLDVSHRVMKTDTALDFLYELYAFKQLVGSVVLTRYNNRT
YEIDDIAWDKNPRCAFQDHAGSQITFVDYYKRAYDLDITDLEQPLLIHRP
MVCLVPELCAMTGLTDAARSDFKVMKDLAVHTRVPPEKRAESFRKFIQRL
NTTKEASELLHSWGLVLDSRMLDMQGRRLPPEKILFKHSSIVANMEADWS
RECLKEHVISAVSLLDWAVLFVRKDQGKATDFVNMLSKVCPPIGMEVHEP
KMVEVVNDRTESYLRALRELIAPRLQMVVIVFPTSRDDRYSAVKKLCCIE
SPIPSQVLIARTITQQQKLRSVAQKVALQMNAKLGGELWAVEIPLKSCMV
VGIDVYHDKSYGNKSIAGFVASTNPSFTRWYSRTAMQELIHELKLCMQAA
LKKYNEMNQSLPERIIVFRDGVGEGREEYVSEFEVPQFNSCFSIFGENYC
PKLAVVVVQKRITTRIFGRSGHSYDNPPPGVIVDHTITKSYDFYLVSQHV
RQGTVSPTYYRVIYDKSGLKPDHLQRLTYKLTHMYYNWPGTIRTPAPCKY
AHKLAFLVGKSLHRDPAHELSDRLFFL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7yg6 Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7yg6 Structure basis of mammalian Piwi-piRNA silencing machinery
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Q735 L987
Binding residue
(residue number reindexed from 1)		Q479 L727
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7yg6, PDBe:7yg6, PDBj:7yg6
PDBsum7yg6
PubMed38658622
UniProtD5MRY8

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