Structure of PDB 7yc6 Chain A Binding Site BS02

Receptor Information
>7yc6 Chain A (length=183) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVILDNGGQYVHRIHRSLKYIGVSSKIVPNTTPLEEIESNKEVKGIILS
GGPDIEKAKNCIDIALNAKLPILGICLGHQLIALAYGGEVGRAALTKVYV
DKENPLFKNVPREFNAWASHKDEVKKVPEGFEILAHSDICQVEAMKHKTK
PIYGVQFHPEVAHTEYGNEILKNFCKVCGYKFE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7yc6 Chain A Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7yc6 Crystal structure of D110P mutant of GATase subunit of Methanocaldococcus jannaschii GMP synthetase
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E128 C145
Binding residue
(residue number reindexed from 1)		E123 C140
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.5.2: GMP synthase (glutamine-hydrolyzing).
Gene Ontology
Molecular Function
GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006177 GMP biosynthetic process
GO:0006541 glutamine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7yc6, PDBe:7yc6, PDBj:7yc6
PDBsum7yc6
PubMed
UniProtQ58970|GUAAA_METJA GMP synthase [glutamine-hydrolyzing] subunit A (Gene Name=guaAA)

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