Structure of PDB 7y9y Chain A Binding Site BS02

Receptor Information
>7y9y Chain A (length=1482) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNT
KGRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQ
LRQRSTLRWTDKNPCPDNAETYCPFCELLGRSFRIHFGNLSLPGKPDFDG
PKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDNKVSAE
ARKLLCDSLKFTDRLCGALCVIRFDNLAEKTAEQIISILDDNKKTEYTRL
LADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGVTIRQILTTSADTKEL
KNAGKWREFCEKLGEALYLKSKDSRSVSIGSVLKETVVCGELVAKTPFFF
GAIDEDAKQTALQVLLTPDNKYRLPRSAVRGILRRDLQTYFDSPCNAELG
GRPCMCKTCRIMRGITVMDARSEYNAPPEIRHRTRINPFTGTVAEGALFN
MEVAPEGIVFPFQLRYRGSEDGLPDALKTVLKWWAEGQAFMSGAASTGKG
RFRMENAKYETLDLSDENQRNDYLKNWGWRDEKGLEELKKRLNSGLPEPG
NYRDPKWHEINVSIEMASPFINGDPIRAAVDKRGTAVVTFVKYKAEGEEA
KPVCAYKAESFRGVIRSAVARIHCECLLCQIFGSEYEAGKIRFEDLVFES
DPEPVTFDHVAIDRFTGGAADKKKFDDSPLPGSPARPLMLKGSFWIRRDV
LEDEEYCKALGKALADVNNGLYPLGGKSAIGYGQVKSLGIKGDDKRISRL
MNVAVPEKPKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQKFHEG
RLTGKIRCKLITKTPLIVPDTSNDDFFYHKSYAFFRLHKQIMIPGSELRG
MVSSVYETVTNSCFRIFDETKRLSWRMDAQDFLPGRVGKHIQKFSETARV
PFYDKTQKHFDILDEQEIAGEKPVRMWVKRFIKRLSLVDPAWKRRKEGIA
TFIEQKNGSYYFNVVTNNGCTSFHLWHKPDNFDQEKLEGIQNGEKLDCWV
RDSRYQKAFQEIPENDPDGWECKEGYLHVVGPSKVEFSDKKGDVINNFQG
TLPSVPNDWKTIRTNDFKNRKRKNEPVFCCEDDKGNYYTMAKYCETFFFD
LKENEEYEIPEKARIKYKELLRVYNNNPQAVPESVFQSRVARENVEKLKS
GDLVYFKHNEKYVEDIVPVRISRTVDDRMIGKRMSADLRPCHGDWVEDGD
LSALNAYPEKRLLLRHPKGLCPACRLFGTGSYKGRVRFGFASLENDPEWL
IPGKNPGDPFHGGPVMLSLLERPRPTWSIPGSDNKFKVPGRKFYVHHHAW
KTIKDGNHPTTGKAIEQSPNNRTVEALAGGNSFSFEIAFENLKEWELGLL
IHSLQLEKGLAHKLGMAKSMGFGSVEIDVESVRLRKDWKQWRNGNSEIPN
WLGKGFAKLKEWFRDELDFIENLKKLLWFPEGDQAPRVCYPMLRKKDDPN
GNSGYEELKDGEFKKEDRQKKLTTPWTPWASS
Ligand information
>7y9y Chain D (length=23) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uacccaugucgaagacaacaaag
.......................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y9y RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
Resolution2.77 Å
Binding residue
(original residue number in PDB)
Y281 R283 H306 Y313 K364 A429 E513 G514 L516 F517 E717 D753 K754 K756 F757 A981 R1125 Q1127 K1155 E1157 F1158 S1159 D1160 P1249 Q1250 L1391 R1393 N1441 R1443 R1565
Binding residue
(residue number reindexed from 1)
Y247 R249 H272 Y279 K322 A361 E445 G446 L448 F449 E635 D671 K672 K674 F675 A879 R1004 Q1006 K1034 E1036 F1037 S1038 D1039 P1128 Q1129 L1270 R1272 N1320 R1322 R1444
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:7y9y, PDBe:7y9y, PDBj:7y9y
PDBsum7y9y
PubMed36423304
UniProtA0A401FT36

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