Structure of PDB 7y9x Chain A Binding Site BS02

Receptor Information
>7y9x Chain A (length=1458) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNT
KGRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQ
LRQRSTLRWTDKNPCPDNAETYCPFCELLGRSFRIHFGNLSLPGKPDFDG
PKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDNKVSAE
ARKLLCDSLKFTDRLCGALCVIRFDNLAEKTAEQIISILDDNKKTEYTRL
LADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGVTIRQILTTSADTKEL
KNAGKWREFCEKLGEALYLKSKDMSGGLKITRRILGDAEFHGKPDRLEKS
RSVSIGSVLKETVVCGELVAKTPFFFGAIDEDAKQTALQVLLTPDNKYRL
PRSAVRGILRRDLQTYFDSPCNAELGGRPCMCKTCRIMRGITVMDARSEY
NAPPEIRHRTRINPFTGTVAEGALFNMEVAPEGIVFPFQLRYRGSEDGLP
DALKTVLKWWAEGQAFMSGAASTGKGRFRMENAKYETLDLSDENQRNDYL
KNWGWRDEKGLEELKKRLNSGLPEPGNYRDPKWHEINVSIEMASPFINGD
PIRAAVDKRGTAVVTFVKYKAEGEEAKPVCAYKAESFRGVIRSAVARIHM
EDGVPLTELTHSDCECLLCQIFGSEYEAGKIRFEDLVFESDPEPVTFDHV
AIDRFTGGAAAKKKFDDSPLPGSPARPLMLKGSFWIRRDVLEDEEYCKAL
GKALADVNNGLYPLGGKSAIGYGQVKSLGIKGDDKRISRLMNTDVAVPEK
PKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQKFHEGRLTGKIRC
KLITKTPLIVPDTSNDDFFRYHKSYAFFRLHKQIMIPGSELRGMVSSVYE
TVTNSCFRIFDETKRLSWRMDADLQDFLPGRVTADGKHIQKFSETARVPF
YDKTQKHFDILDEQEIAGEKPVRMWVKRFRYQKAFQEIPENDPDGWECKE
GYLHVVGPSKVEFSDKKGDVINNFQGTLPSVPNDWKTIRTNDFKNRKRKN
EPVFCCEDDKGNYYTMAKYCETFFFDLKENEEYEIPEKARIKYKELLRVY
NNNPQAVPESVFQSRVARENVEKLKSGDLVYFKHNEKYVEDIVPVRISRT
VDDRMIGKRMSADLRPCHGDWVEDGDLSALNAYPEKRLLLRHPKGLCPAC
RLFGTGSYKGRVRFGFASLENDPEWLIPGKNPGDPFHGGPVMLSLLERPR
PTWSIPGSDNKFKVPGRKFYVHHHAWKTIKDGNHPTTGKAIEQSPNNRTV
EALAGGNSFSFEIAFENLKEWELGLLIHSLQLEKGLAHKLGMAKSMGFGS
VEIDVESVRLRKDWKQWRNGNSEIPNWLGKGFAKLKEWFRDELDFIENLK
KLLWFPEGDQAPRVCYPMLRKKDDPNGNSGYEELKDGEFKKEDRQKKLTT
PWTPWASS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7y9x Chain A Residue 1701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7y9x RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease.
Resolution2.49 Å
Binding residue
(original residue number in PDB)		C463 C472 C474 C477
Binding residue
(residue number reindexed from 1)		C421 C430 C432 C435
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:7y9x, PDBe:7y9x, PDBj:7y9x
PDBsum7y9x
PubMed36423304
UniProtA0A401FT36

[Back to BioLiP]