Structure of PDB 7y83 Chain A Binding Site BS02

Receptor Information
>7y83 Chain A (length=1221) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKGHHLWDIKVQGTALRTK
LKELWQSNKDIGWRKFTEMLGSNLYLIYKKETGGVSTRFRILGDTEYYSS
DLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKSLVINEH
TSFNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKV
CIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGL
TFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALK
DIKIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEER
ECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKR
VYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMC
IIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKF
DTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSK
GGVGYGWVAGISIINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYR
EKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHK
NYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSASKTLG
GKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITR
GNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLE
IRETVQPERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIA
HKLGKGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIEWSG
PQWHVIPHIDKLYKLLWVPFLEPDVRYPVLNEESKGYIEGSDYTYKKLGD
KDNLPYKTRVKGLTTPWSPWN
Ligand information
>7y83 Chain C (length=23) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uccggggcagaaaauuggcaugg
.......................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y83 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.93 Å
Binding residue
(original residue number in PDB)		K187 K292 R294 I295 K320 H328 Y367 K371 S378 R382 F458 V540 D542 G543 L545 F546 D698 E748 D749 E761 H762 A799 D801 K802 A803 K804 F805 T1423 L1459 S1461 R1463 R1505 L1648
Binding residue
(residue number reindexed from 1)		K177 K255 R257 I258 K283 H286 Y325 K329 S336 R340 F403 V485 D487 G488 L490 F491 D643 E693 D694 E706 H707 A744 D746 K747 A748 K749 F750 T977 L1013 S1015 R1017 R1059 L1180
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7y83, PDBe:7y83, PDBj:7y83
PDBsum7y83
PubMed36477448
UniProtA0A0B0EGF3

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