Structure of PDB 7y82 Chain A Binding Site BS02

Receptor Information
>7y82 Chain A (length=1341) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETTEYYSSDLFIPVT
PPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEVINEHTSFNILLD
KENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRIT
LKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRY
RGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWD
LNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEERECLFPYKE
NLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNA
IEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHE
SSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGS
PKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWV
AGISIDDNVINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDI
ITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKF
FNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSWRMNADEKDY
VRDKNRVFLNAANNNRQYLNNIKKSNHDLYLQYLKGEKKIRFGYPVDDQI
KKNYEDILDSYDGIKDQEVAERFDTFTRGSKLKVGDLVYFHIIDSLIPVR
ISRKCASKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAK
YENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHN
GWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVRFENLREWELGLL
LQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYIN
KGYQKLIEWSGLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEE
SKGYIEGSDYTYKKLGDKDNLPYKTRVKGLTTPWSPWNPFQ
Ligand information
>7y82 Chain C (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggaguccggggcagaaaauugggu
.........................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y82 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.83 Å
Binding residue
(original residue number in PDB)		A188 K189 K292 R294 K320 R323 K325 H328 Y367 K371 T387 S457 F458 G543 L545 F546 D698 E761 D801 K802 A803 K804 F805 A1034 K1345 E1460 S1461 L1648 N1649 E1651
Binding residue
(residue number reindexed from 1)		A178 K179 K255 R257 K283 R286 K288 H291 Y330 K334 T338 S394 F395 G480 L482 F483 D635 E698 D738 K739 A740 K741 F742 A945 K1015 E1125 S1126 L1297 N1298 E1300
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7y82, PDBe:7y82, PDBj:7y82
PDBsum7y82
PubMed36477448
UniProtA0A0B0EGF3

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