Structure of PDB 7y43 Chain A Binding Site BS02
Receptor Information
>7y43 Chain A (length=79) Species:
9606
(Homo sapiens) [
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KLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLE
LSVKDGTILKVSNKGLNSYKDPDNPGRIA
Ligand information
>7y43 Chain C (length=14) [
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ggagtgcgcactcc
Receptor-Ligand Complex Structure
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PDB
7y43
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.
Resolution
1.5 Å
Binding residue
(original residue number in PDB)
K21 K24 Q25 R26 R79
Binding residue
(residue number reindexed from 1)
K19 K22 Q23 R24 R77
Enzymatic activity
Enzyme Commision number
2.3.1.48
: histone acetyltransferase.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
View graph for
Molecular Function
External links
PDB
RCSB:7y43
,
PDBe:7y43
,
PDBj:7y43
PDBsum
7y43
PubMed
36537216
UniProt
Q92794
|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)
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