Structure of PDB 7y1u Chain A Binding Site BS02

Receptor Information
>7y1u Chain A (length=723) Species: 1448857 (Campylobacter corcagiensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIIYTYTDEAPALATYSLYPIIKHFLEKASIDITTADISLAGRILANFPE
YLNEDQKVKDYLQILGELTKKSDANIIKLPNISASLPQLLDCIKELQDKG
FKVPNYPNEPKDEKERLIKERYAKILGSAVNPVLREGNSIRRAAGAVKEY
AKANPHSNGVWNKNTKTKVCYMDGGDFYSNEKSKIFENSTNLEVEFIPKN
GDKKLLKELNIQAGEVVDATFMSAKKLDEFIAKSIDLAKDESLLYSVHLK
ATMMKVSDPVIFGHFVKGFFDEVFTEFQGELKALGVNPNNGLGDLFIKIE
NSKLKDKILAKFDEIYASRPSLSMVNSDKGITNLHVPSDVIIDASMPAML
RNSGRLWDKDAKEVEALAVIPDKSYAVVYEAMIKDLKENGTLDPSQIGSV
TNIGLMAKKAEEYGSHDKTFIIESDGQIIVNDSNGEEIFRFEVEKGDIFR
MTQTKSEPIKNWVKLAFDRAKLTGEKAIFWLDEKRAHDRNLIMLVKDELK
KYDLKGFDYEILDPFSATLKTNQTIREGKNIISVTGNVLRDYLTDLYPIL
ELGTSAKMLSIVPLLNGGGMFETGAGGSAPKHVEQLVSENHLRWDSLGEF
MALIVSLEHLGTQNAKILAKALDKAVSRFLKEDKSPKRRAGEPDNRNSHF
YLAMYFADELTKTELGNIYSDLALNLKNNEAKINDELLSVQGKSVDLGGY
YKFDDEKASLVMRPSKTLNDIIN
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7y1u Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y1u Crystal structure of isocitrate dehydrogenase from Campylobacter corcagiensis
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D343 D545 G576
Binding residue
(residue number reindexed from 1)		D343 D545 G576
Annotation score1
Enzymatic activity
Enzyme Commision number 1.1.1.42: isocitrate dehydrogenase (NADP(+)).
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006097 glyoxylate cycle
GO:0006099 tricarboxylic acid cycle

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7y1u, PDBe:7y1u, PDBj:7y1u
PDBsum7y1u
PubMed
UniProtA0A7M1LFL5

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