Structure of PDB 7xps Chain A Binding Site BS02

Receptor Information
>7xps Chain A (length=371) Species: 531310 (Marinactinospora thermotolerans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RDISTAVVVTTISDGGFLDRLAPALRDAGARLIVIPDRNTGPALFAACER
HRRLGLDVVCPSVAEQQDLLERLAVPDLIPYHSDNRRNVGYLMAWMEGFD
VIVSMDDDNLPTTDDFVERHQVVCQGPRTQPVTASSDGWFNNCALLEVEP
TEVFPRGFPFHARPAHAQARTSVCERPADVRINAGLWLGDPDVDAITRLA
VRPNALAHSGGSVVLAEGTWCPVNSQNTAVHRDALPAYYFLRMGQPVDGV
PMERFGDIFSGYFVQVCAQHLGHAVRFGDPVVEHPRNEHDLLDDLHKEVP
AVRLLDDILDHLRDHPLEGGDYLETYESLSYALQEIAERVNGRAWSPDAR
AFLHRSAHLMRSWTGALRTVA
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7xps Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7xps Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D111 H287
Binding residue
(residue number reindexed from 1)		D108 H284
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7xps, PDBe:7xps, PDBj:7xps
PDBsum7xps
PubMed36642179
UniProtG8HX37

[Back to BioLiP]