Structure of PDB 7wku Chain A Binding Site BS02

Receptor Information

>7wku Chain A (length=304) Species: 1586324 (Porcine deltacoronavirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGDQ
WTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPDY
KFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGYT
LKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYYT
DNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTNM
SYIMGLSQTARVPVERILNTIIQLTTNRDGACIMGSYDFECDWTPEMVYN
QAPI

Ligand information

>7wku Chain K (length=5) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gAVLa

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7wku The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
Resolution	2.6 Å
Binding residue (original residue number in PDB)	S25 A26 L27
Binding residue (residue number reindexed from 1)	S25 A26 L27

Enzymatic activity

Enzyme Commision number

2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.

Gene Ontology

	Molecular Function
GO:0008233	peptidase activity

	Biological Process
GO:0019082	viral protein processing

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Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:7wku, PDBe:7wku, PDBj:7wku
PDBsum	7wku
PubMed	35336895
UniProt	A0A140ESF0

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