Structure of PDB 7wh0 Chain A Binding Site BS02

Receptor Information
>7wh0 Chain A (length=529) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEAEGFPRLFHNFENVPEPKECKKVGSVPSYLTGTMLRNGPGMFTVGEEE
YKHWFDGLGFMQRYHFEDGKMFYSARYLESEAYTKTVEAQRIVAGTFGTL
SFPDPCKTIFSKYFSEFMNHSEKHDNSNVAFTPVGDSLYACTETPHMYRV
DLDTLKTLEAADFSKFVAVHSCTAHQLYDENGDVYNIGSRFGPESAHVFT
VTKNPKNQKSENDHSWEHTSKIGEIKASDPLYPTYMHSFGMSENYLVMFE
SPVRLHLQKYLLSEFVRATYHDCLEWHGDKDVSIFILNKKTGEQLPLTLK
MNPFFTFHHANTFEKDGCLVMDYCRIENAGKFDTLLISNMKTGEFQYDAK
FLPYLTRVIVPMSVSSSAKPGDNLLKSVPWASGCTSILQDDGSIRLTERR
VCETSMEFPRYHWEKINMKEYRYVFGSTVFGRIDGNLAGVVKADLKFGNH
LIWNRENPHQICGEPIFVPNPEGIEEDDGILIVPIMSSSEKQVPFVLILD
AKTLEETARFEIPEARIPLGFHAFYKPKN
Ligand information
Ligand IDOXD
InChIInChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)
InChIKeyMUBZPKHOEPUJKR-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC(=O)C(O)=O
ACDLabs 10.04O=C(O)C(=O)O
OpenEye OEToolkits 1.5.0C(=O)(C(=O)O)O
FormulaC2 H2 O4
NameOXALIC ACID
ChEMBLCHEMBL146755
DrugBankDB03902
ZINCZINC000006021239
PDB chain7wh0 Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7wh0 Structural and Functional Analysis of Nonheme Iron Enzymes BCMO-1 and BCMO-2 from Caenorhabditis elegans .
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H237 H308 F521 H522
Binding residue
(residue number reindexed from 1)		H237 H308 F521 H522
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003834 beta-carotene 15,15'-dioxygenase activity
GO:0010436 carotenoid dioxygenase activity
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872 metal ion binding
Biological Process
GO:0016121 carotene catabolic process
GO:0042574 retinal metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7wh0, PDBe:7wh0, PDBj:7wh0
PDBsum7wh0
PubMed35223999
UniProtQ9U2E4

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