Structure of PDB 7wah Chain A Binding Site BS02

Receptor Information
>7wah Chain A (length=1473) Species: 45657 (Desulfonema ishimotonii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTTTMKISIEFLEPFRMTKWQESTRRNKNNKEFVRGQAFARWHRNKKDNT
KGRPYITGTLLRSAVIRSAENLLTLSDGKISEKTCCPGKFDTEDKDRLLQ
LRQRSTLRWTDKNPCPDNAETYCPFCELLGRSFRIHFGNLSLPGKPDFDG
PKAIGSQRVLNRVDFKSGKAHDFFKAYEVDHTRFPRFEGEITIDNKVSAE
ARKLLCDSLKFTDRLCGALCVIRFDNLAEKTAEQIISILDDNKKTEYTRL
LADAIRSLRRSSKLVAGLPKDHDGKDDHYLWDIGVTIRQILTTSADTKEL
KNAGKWREFCEKLGEALYLKSKSVLKETVVCGELVAKTPFFFGAIDEDAK
QTALQVLLTPDNKYRLPRSAVRGILRRDLQTYFDSPCNAELGGRPCMCKT
CRIMRGITVMDARSEYNAPPEIRHRTRINPFTGTVAEGALFNMEVAPEGI
VFPFQLRYRGSEDGLPDALKTVLKWWAEGQAFMSGAASTGKGRFRMENAK
YETLDLSDENQRNDYLKNWGWRDEKGLEELKKRLNSGLPEPGNYRDPKWH
EINVSIEMASPFINGDPIRAAVDKRGTAVVTFVKYKAEGEEAKPVCAYKA
ESFRGVIRSAVARIHMEDGVPLTELTHSDCECLLCQIFGSEYEAGKIRFE
DLVFESDPEPVTFDHVAIDRFTGGAAAKKKFDDSPLPGSPARPLMLKGSF
WIRRDVLEDEEYCKALGKALADVNNGLYPLGGKSAIGYGQVKSLGIKGDD
KRISRLMNAVPEKPKTDAEVRIEAEKVYYPHYFVEPHKKVEREEKPCGHQ
KFHEGRLTGKIRCKLITKTPLIVPDTSNDDFFRPYHKSYAFFRLHKQIMI
PGSELRGMVSSVYETVTNSCFRIFDETKRLSWRMDADQDFLPGRVTADGK
HIQKFSETARVPFYDKTQKHFDILDEQEIAGEKPVRMWVKRFIKRLSLVD
PAKHWKRRKEGIATFIEQKNGSYYFNVVTNNGCTSFHLWHKPDNFDQEKL
EGIQNGEKLDCWVRDSRYQKAFQEIPENDPDGWECKEGYLHVVGPSKVEF
SDKKGDVINNFQGTLPSVPNDWKTIRTNDFKNRKRKNEPVFCCEDDKGNY
YTMAKYCETFFFDLKENEEYEIPEKARIKYKELLRVYNNNPQAVPESVFQ
SRVARENVEKLKSGDLVYFKHNEKYVEDIVPVRISRTVDDRMIGKRMSAD
LRPCHGDWKGLCPACRLFGTGSYKGRVRFGFASLENDPEWLIPGKNPGDP
FHGGPVMLSLLERPRPTWSIPGSDNKFKVPGRKFYVHHHAWKTIKDGNHP
TTGKAIEQSPNNRTVEALAGGNSFSFEIAFENLKEWELGLLIHSLQLEKG
LAHKLGMAKSMGFGSVEIDVESVRLRKDWKQWRNGNSEIPNWLGKGFAKL
KEWFRDELDFIENLKKLLWFPEGDQAPRVCYPMLRKKDDPNGNSGYEELK
DGEFKKEDRQKKLTTPWTPWASS
Ligand information
>7wah Chain D (length=23) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uacccaugucgaagacaacaaag
.......................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wah Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		Y281 R283 H306 Y313 G514 L516 F517 E717 A753 K754 K755 K756 F757 A981 R1125 E1157 S1159 D1160 Q1250 R1393 N1441 R1443 R1565
Binding residue
(residue number reindexed from 1)		Y247 R249 H272 Y279 G438 L440 F441 E641 A677 K678 K679 K680 F681 A886 R1017 E1049 S1051 D1052 Q1142 R1263 N1311 R1313 R1435
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:7wah, PDBe:7wah, PDBj:7wah
PDBsum7wah
PubMed35643083
UniProtA0A401FT36

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