Structure of PDB 7vs9 Chain A Binding Site BS02

Receptor Information
>7vs9 Chain A (length=310) Species: 999890 (Norovirus Hu/GI/Vancouver730/2004/CAN) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKQFSVPNLPLNVMSNSRVPSLLNAMVVSPDQAQVVQFQNGRCTLDGQML
GTTTVSASCVARFRGKTFQAPDNRLGINLAEISGEPYHAFESPAPLGFPD
FGDGDWHVTATKVTPSQLEANDPVVVGNVQPYNPQFAPHLGTLVVENPTP
DQVATGTDLLFNITWLSNRANNRFNPWVIPNYGSTLTEAAQLAPSIFPPG
FGETIVYFNSTFPAVGATTHAAIPCLLPQEFVAHFVNEQAPIRGEAALLH
YIDPDTHRNLGEFKIYPEGFVTCVPNVGGTGPQSLPTNGVFVFVSWVSRY
YQLKPVGTAG
Ligand information
Ligand IDGAL
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3+,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-FPRJBGLDSA-N
SMILES
SoftwareSMILES
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O
OpenEye OEToolkits 1.7.2C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
OpenEye OEToolkits 1.7.2C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
FormulaC6 H12 O6
Namebeta-D-galactopyranose;
beta-D-galactose;
D-galactose;
galactose
ChEMBLCHEMBL300520
DrugBank
ZINCZINC000002597049
PDB chain7vs9 Chain C Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7vs9 Lewis fucose is a key moiety for the recognition of histo-blood group antigens by GI.9 norovirus, as revealed by structural analysis.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		D335 H337 S397 N398 A400
Binding residue
(residue number reindexed from 1)		D105 H107 S167 N168 A170
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links