Structure of PDB 7v39 Chain A Binding Site BS02

Receptor Information
>7v39 Chain A (length=203) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPR
VVL
Ligand information
Ligand IDHGB
InChIInChI=1S/C7H5O2.Hg.H2O/c8-7(9)6-4-2-1-3-5-6;;/h2-5H,(H,8,9);;1H2/q;+1;/p-1
InChIKeyWMHRYLDWLOGHSG-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)c1ccc([Hg]O)cc1
OpenEye OEToolkits 1.5.0c1cc(ccc1C(=O)O)[Hg]O
CACTVS 3.341O[Hg]c1ccc(cc1)C(O)=O
FormulaC7 H6 Hg O3
Name4-(HYDROXYMERCURY)BENZOIC ACID
ChEMBL
DrugBankDB01671
ZINC
PDB chain7v39 Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7v39 Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Q379 C409 R551 A552
Binding residue
(residue number reindexed from 1)		Q17 C47 R185 A186
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:7v39, PDBe:7v39, PDBj:7v39
PDBsum7v39
PubMed34977900
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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