Structure of PDB 7v38 Chain A Binding Site BS02

Receptor Information
>7v38 Chain A (length=203) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEKKKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPR
VVL
Ligand information
Ligand IDPMB
InChIInChI=1S/C6H5O3S.Hg/c7-10(8,9)6-4-2-1-3-5-6;/h2-5H,(H,7,8,9);
InChIKeyKQAOIKIZSJJTII-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc(ccc1S(=O)(=O)O)[Hg]
CACTVS 3.341O[S](=O)(=O)c1ccc([Hg])cc1
ACDLabs 10.04[Hg]c1ccc(cc1)S(=O)(=O)O
FormulaC6 H5 Hg O3 S
NamePARA-MERCURY-BENZENESULFONIC ACID
ChEMBL
DrugBankDB02983
ZINC
PDB chain7v38 Chain A Residue 602 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7v38 Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites.
Resolution2.403 Å
Binding residue
(original residue number in PDB)		Q379 C409 R551 A552
Binding residue
(residue number reindexed from 1)		Q17 C47 R185 A186
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:7v38, PDBe:7v38, PDBj:7v38
PDBsum7v38
PubMed34977900
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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