Structure of PDB 7usf Chain A Binding Site BS02

Receptor Information
>7usf Chain A (length=265) Species: 11757 (Mouse mammary tumor virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALESAQESHALHHQNAAALRFQFHITREQAREIVKLCPNCPDWGHAPQLG
VNPRGLKPRVLWQMDVTHVSEFGKLKYVHVTVDTYSHFTFATARTGEATK
DVLQHLAQSFAYMGIPQKIKTDNAPAYVSRSIQEFLARWKISHVTGIPYN
PQGQAIVERTHQNIKAQLNKLQKAGKYYTPHHLLAHALFVLNHVNMDNQG
HTAAERHWGPISADPKPMVMWKDLLTGSWKGPDVLITAGRGYACVFPQDA
ESPIWVPDRFIRPFT
Ligand information
>7usf Chain J (length=40) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caggtcggccgactgcggcactcgagctacttccctgttt
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7usf B-to-A transition in target DNA during retroviral integration.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		H68 P151 E158 Q162 R240
Binding residue
(residue number reindexed from 1)		H68 P151 E158 Q162 R240
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7usf, PDBe:7usf, PDBj:7usf
PDBsum7usf
PubMed35947647
UniProtP03365|POL_MMTVB Gag-Pro-Pol polyprotein (Gene Name=gag-pro-pol)

[Back to BioLiP]