Structure of PDB 7ujd Chain A Binding Site BS02

Receptor Information
>7ujd Chain A (length=577) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSE
DVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYSARMNLASSF
VNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGL
TQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDFVLHNSNT
MRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIA
VGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAI
LAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHQGVAVLGIALIA
MGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLS
KFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM
VRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIIL
GKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAFQTHTTPVLLAH
GERAELATEEFLPVTPILEGFVILRKN
Ligand information
>7ujd Chain D (length=26) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YYSIHASIYPYYSYTSRYQSSSYGYG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ujd Targeted degradation via direct 26S proteasome recruitment.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
H677 Y681 E683
Binding residue
(residue number reindexed from 1)
H366 Y370 E372
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7ujd, PDBe:7ujd, PDBj:7ujd
PDBsum7ujd
PubMed36577875
UniProtQ13200|PSMD2_HUMAN 26S proteasome non-ATPase regulatory subunit 2 (Gene Name=PSMD2)

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