Structure of PDB 7uat Chain A Binding Site BS02

Receptor Information
>7uat Chain A (length=226) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIAHNLAQVRDKISAAATRCGRSPEEITLLAVSATKPASAIAEAIDAGQR
QFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAV
AELPRLRLRGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSL
GMSDDMEAAIAAGSTMVRIGTAIFGA
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain7uat Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7uat Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		W99 R161
Binding residue
(residue number reindexed from 1)		W97 R159
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030170 pyridoxal phosphate binding
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:7uat, PDBe:7uat, PDBj:7uat
PDBsum7uat
PubMed36218140
UniProtP67080|PLPHP_ECOLI Pyridoxal phosphate homeostasis protein (Gene Name=yggS)

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