Structure of PDB 7tv0 Chain A Binding Site BS02

Receptor Information
>7tv0 Chain A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLN
LPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPG
DDIVLMAEALEKLFLQKINELPTEETEIMIVQAK
Ligand information
>7tv0 Chain G (length=12) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KPSFYVYSRVKN
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7tv0 Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		W81 F83 V87 K91 L92 I146
Binding residue
(residue number reindexed from 1)		W38 F40 V44 K48 L49 I103
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7tv0, PDBe:7tv0, PDBj:7tv0
PDBsum7tv0
PubMed35716662
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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