Structure of PDB 7tdx Chain A Binding Site BS02

Receptor Information
>7tdx Chain A (length=90) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PEFFHNMDYFKYHNMRPPFTYATLIRWAILEAPERQRTLNEIYHWFTRMF
AYFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDEF
Ligand information
Receptor-Ligand Complex Structure
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PDB7tdx The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R337 T341 Y342 N383 H387
Binding residue
(residue number reindexed from 1)		R16 T20 Y21 N62 H66
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7tdx, PDBe:7tdx, PDBj:7tdx
PDBsum7tdx
PubMed35926508
UniProtQ99JB6|FOXP3_MOUSE Forkhead box protein P3 (Gene Name=Foxp3)

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