Structure of PDB 7t91 Chain A Binding Site BS02
Receptor Information
>7t91 Chain A (length=67) Species:
9606
(Homo sapiens) [
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ETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFK
AQYMLVVHMRRHTGEKP
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
7t91 Chain A Residue 402 [
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Receptor-Ligand Complex Structure
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PDB
7t91
Crystal structure of Zinc finger motif 1 and 2 of GLI1 DNA binding region
Resolution
2.05 Å
Binding residue
(original residue number in PDB)
C270 C275 H291 H295
Binding residue
(residue number reindexed from 1)
C37 C42 H58 H62
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000977
RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0008270
zinc ion binding
Biological Process
GO:0006357
regulation of transcription by RNA polymerase II
Cellular Component
GO:0005634
nucleus
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Molecular Function
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Cellular Component
External links
PDB
RCSB:7t91
,
PDBe:7t91
,
PDBj:7t91
PDBsum
7t91
PubMed
UniProt
P08151
|GLI1_HUMAN Zinc finger protein GLI1 (Gene Name=GLI1)
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