Structure of PDB 7t19 Chain A Binding Site BS02

Receptor Information
>7t19 Chain A (length=438) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDTY
IIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNYV
ARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRLN
IFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCTV
SIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGHS
TLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDEE
SLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLNE
INKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFGI
IATEMKSLYRTLGCPPMELRGLALQFNKLVDVGPDNNQ
Ligand information
Receptor-Ligand Complex Structure
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PDB7t19 Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1.
Resolution2.01 Å
Binding residue
(original residue number in PDB)		Y319 H322 S323 R324 L325 H326 S329 H393 G394 T395 K396 N397 S398 D399 K590 R620 K621 S624 I625 D626 N628 W629 K681 Y682 G684 M685 G686
Binding residue
(residue number reindexed from 1)		Y13 H16 S17 R18 L19 H20 S23 H87 G88 T89 K90 N91 S92 D93 K284 R314 K315 S318 I319 D320 N322 W323 K375 Y376 G378 M379 G380
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7t19, PDBe:7t19, PDBj:7t19
PDBsum7t19
PubMed35610266
UniProtP12689|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)

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