Structure of PDB 7t18 Chain A Binding Site BS02

Receptor Information
>7t18 Chain A (length=439) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RIVACDDPDFLTSYFAHSRLHHLSAWKANLKDKFLNENIHKYTKITDKDT
YIIFHIDFDCFFATVAYLCRSSSFSACDFKRDPIVVCHGTKNSDIASCNY
VARSYGIKNGMWVSQAEKMLPNGIKLISLPYTFEQFQLKSEAFYSTLKRL
NIFNLILPISIDEAVCVRIIPDNIHNTNTLNARLCEEIRQEIFQGTNGCT
VSIGCSDSLVLARLALKMAKPNGYNITFKSNLSEEFWSSFKLDDLPGVGH
STLSRLESTFDSPHSLNDLRKRYTLDALKASVGSKLGMKIHLALQGQDDE
ESLKILYDPKEVLQRKSLSIDINWGIRFKNITQVDLFIERGCQYLLEKLN
EINKTTSQITLKLMRRCKDAPIEPPKYMGMGRCDSFSRSSRLGIPTNEFG
IIATEMKSLYRTLGCPPMELRGLALQFNKLVDVGPDNNQ
Ligand information
Receptor-Ligand Complex Structure
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PDB7t18 Mechanism of nucleotide discrimination by the translesion synthesis polymerase Rev1.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		Y319 F320 H322 S323 R324 L325 H326 S329 H393 G394 T395 K396 N397 S398 D399 K590 R620 K621 S622 S624 I625 D626 N628 W629 K681 Y682 G684 M685 G686
Binding residue
(residue number reindexed from 1)		Y14 F15 H17 S18 R19 L20 H21 S24 H88 G89 T90 K91 N92 S93 D94 K285 R315 K316 S317 S319 I320 D321 N323 W324 K376 Y377 G379 M380 G381
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7t18, PDBe:7t18, PDBj:7t18
PDBsum7t18
PubMed35610266
UniProtP12689|REV1_YEAST DNA repair protein REV1 (Gene Name=REV1)

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