Structure of PDB 7t0v Chain A Binding Site BS02

Receptor Information
>7t0v Chain A (length=568) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTPPTKVSILDIAGVDDTLQRLLKEVWFPLRGGEACEKMGYRYDNGVLLH
GPSGCGKTTLAHAIAGSIGVAFIPVSAPSVIGGTSGESEKNIRDVFDEAI
RLAPCLIFLDQIDAIAGRRESANKGMESRIVAEIMNGMDRIRQNTPLGKN
VVVLAATNRPEFLDPAIRRRFSVEIDMGMPSERAREQILRSLTRDLSLAD
DINFKELAKMTPGYVGSDLQYVVKAAVSESFQANIDSLLAQARAKHPVSQ
PQRDWLLLEAHRDEEVSWPSTKITMEQFRKAVSLVQPASKREGFSTIPDT
TWSHVGALEDVRKKLEMSIIGPIKNPELFTRVGIKPAAGILLWGPPGCGK
TLVAKAVANESKANFISIKGPELLNKYVGESERAVRQLFSRAKSSAPCIL
FFDQMDALVPRRDDSLSDASARVVNTLLTELDGVGDRSGIYVIGATNRPD
MIDEAIRRPGRLGTSIYVGLPSAEDRVKILKTLYRNTVTTDADLEKVALD
LRCTGFSGADLGNLMQAAAQACLERVYTQRQQKRKEEEIEPVITMEDWEK
ALNEVKPSVKDPEKYMHS
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain7t0v Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t0v Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Resolution3.67 Å
Binding residue
(original residue number in PDB)		G504 P544 G545 C546 G547 K548 T549 L550 N645 I677 L681 G733 A734
Binding residue
(residue number reindexed from 1)		G306 P346 G347 C348 G349 K350 T351 L352 N447 I479 L483 G508 A509
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:1990275 preribosome binding
Biological Process
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t0v, PDBe:7t0v, PDBj:7t0v
PDBsum7t0v
PubMed36090660
UniProtG0RZG1

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