Structure of PDB 7swl Chain A Binding Site BS02

Receptor Information
>7swl Chain A (length=553) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SILDIAGVDDTLQRLLKEVWFPLRGGEACEKMGYRYDNGVLLHGPSGCGK
TTLAHAIAGSIGVAFIPVSAPSVIGGTSGESEKNIRDVFDEAIRLAPCLI
FLDQIDAIAGGMESRIVAEIMNGMDRIRQNTPLGKNVVVLAATNRPEFLD
PAIRRRFSVEIDMGMPSERAREQILRSLTRDLSLADDINFKELAKMTPGY
VGSDLQYVVKAAVSESFQANIDSLLAQARAKHPADHLANVSQPQRDWLLL
EAHRDEWPSTKITMEQFRKAVSLVQPASKREGFSTIPDTTWSHVGALEDV
RKKLEMSIIGPIKNPELFTRVGIKPAAGILLWGPPGCGKTLVAKAVANES
KANFISIKGPELLNKYVGESERAVRQLFSRAKSSAPCILFFDQMDALVPR
RDDSLSDASARVVNTLLTELDGVGDRSGIYVIGATNRPDMIDEAIRRPGR
LGTSIYVGLPSAEDRVKILKTLYRNTVTTDADLEKVALDLRCTGFSGADL
GNLMQAAAQACLERVYTQRQQKRKEPVITMEDWEKALNEVKPSVKDPEKY
MHS
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain7swl Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7swl Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
Resolution2.88 Å
Binding residue
(original residue number in PDB)		G504 P544 G545 C546 G547 K548 T549 L550 N645 I677 G733 A734
Binding residue
(residue number reindexed from 1)		G295 P335 G336 C337 G338 K339 T340 L341 N436 I468 G497 A498
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7swl, PDBe:7swl, PDBj:7swl
PDBsum7swl
PubMed36090660
UniProtG0RZG1

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