Structure of PDB 7sva Chain A Binding Site BS02

Receptor Information
>7sva Chain A (length=792) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNFAPRPGFGTLGTKCIVKANHFLADLPTKDLNQYDVTITPEVSSKSVNR
AIIAELVRLYKESDLGRRLPAYDGRKSLYTAGELPFTWKEFSVKIERSYK
VAIKFVARANMHHLGEFLAGKRADCPQEAVQILDIVLRELSVKRFCPVGR
SFFSPDIKTPQRLGEGLESWCGFYQSIRPTQMGLSLNIDMASAAFIEPLP
VIEFVAQLLGKDVLSKPLSDSDRVKIKKGLRGVKVEVTHRANVRRKYRVA
GLTTQPTREQHTHLPCLQVSYLPMEACKIVEGQRYTKRLNEKQITALLKV
TCQRPRDRENDILRTVQHNAYDQDPYAKEFGMNISEKLASVEARILPAPW
LKYHENGKEKDCLPQVGQWNMMNKKMINGMTVSRWACVNFSRSVQENVAR
GFCNELGQMCEVSGMEFNPEPVIPIYSARPDQVEKALKHVYHTSMNKTKG
KELELLLAILPDNNGSLYGDLKRICETELGLISQCCLTKHVFKISKQYLA
NVSLKINVKMGGRNTVLVDAISCRIPLVSDIPTIIFGADVTHPENGEESS
PSIAAVVASQDWPEVTKYAGLVCAQAHRQELIQDLYKTWQDPGTVSGGMI
RDLLISFRKATGQKPLRIIFYRAGVSEGQFYQVLLYELDAIRKACASLEP
NYQPPVTFIVVQKRHHTRLFANNHRDKNSTDRSGNILPGTVVDTKICHPT
EFDFYLCSHAGIQGTSRPAHYHVLWDENNFTADGIQSLTNNLCYTYARCT
RSVSIVPPAYYAHLAAFRARFYLEVKPLPALKENVKRVMFYC
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7sva Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7sva Structural basis for RNA slicing by a plant Argonaute.
Resolution3.26 Å
Binding residue
(original residue number in PDB)
D709 H935
Binding residue
(residue number reindexed from 1)
D539 H763
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0035198 miRNA binding
Biological Process
GO:0006417 regulation of translation
GO:0009934 regulation of meristem structural organization
GO:0010072 primary shoot apical meristem specification
GO:0010586 miRNA metabolic process
GO:0031047 regulatory ncRNA-mediated gene silencing
GO:0035019 somatic stem cell population maintenance
GO:0051607 defense response to virus
GO:1902183 regulation of shoot apical meristem development
Cellular Component
GO:0005737 cytoplasm
GO:0009536 plastid
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7sva, PDBe:7sva, PDBj:7sva
PDBsum7sva
PubMed37127820
UniProtQ9XGW1|AGO10_ARATH Protein argonaute 10 (Gene Name=AGO10)

[Back to BioLiP]