Structure of PDB 7rzz Chain A Binding Site BS02

Receptor Information
>7rzz Chain A (length=394) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTWSLMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTSYQKFQ
LFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQEKLKNF
ISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIAICVDQ
NANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQTIIEK
LTADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYIIQHIV
SNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLELLAEMM
DEIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKE
GGYDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLR
Ligand information
>7rzz Chain C (length=15) Species: 6239 (Caenorhabditis elegans) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QHEAPKQLLQLRSEI
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7rzz Bipartite interaction sites differentially modulate RNA-binding affinity of a protein complex essential for germline stem cell self-renewal.
Resolution2.39 Å
Binding residue
(original residue number in PDB)
R441 L444 S445 Q448 E449 G478 Y479 I480 K487 D488 A489 I492
Binding residue
(residue number reindexed from 1)
R269 L272 S273 Q276 E277 G306 Y307 I308 K315 D316 A317 I320
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7rzz, PDBe:7rzz, PDBj:7rzz
PDBsum7rzz
PubMed34908132
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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