Structure of PDB 7qw7 Chain A Binding Site BS02

Receptor Information
>7qw7 Chain A (length=553) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVSRQKATGAHFTPDKLAEVIAKRILDYFKGEKNRVIRVLDPACGDGELL
LAINKVAQSMNIQLELIGVDFDIDAINIANERLSRSGHKNFRLINKDFLE
MEELEPVDIIIANPPYVRTQILGAEKAQKLREKFNLKGRVDLYQAFLVAM
TQQLKSNGIIGVITSNRYLTTKGGESTRKFLVSNFNILEIMDLGDSKFFE
AAVLPAIFFGEKKNKEYQSNVPKFFKIYEQSDIEASSSVNSEFNSLIELL
EVNKSGLYSVEDKTYSISLGKIISPENYKEPWILATEDEYEWFMKVNQNA
YGFIEDFAHVKVGIKTTADSVFIRSDWGELPEEQIPEDKLLRPIISADQA
NKWSVSLVGNNKKVLYTHEIRDGQIKAINLEEFPRAKNYLESHKERLASR
KYVLKANRNWYEIWVPHDPSLWDKPKIIFPDTSPEPKFFYEDKGSVVDGN
CYWIIPKKENSNDILFLIMGICNSKFMSKYHDIAFQNKLYAGRRRYLTQY
VNKYPIPDPESIYSKEIISLVRELVNNKKETQDINEIENRIEKLILRAFD
IES
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7qw7 Structure of M.BseCI DNA methyltransferase from Geobacillus stearothermophilus.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q140 A144 R151 G158 R159 K338 T340 D342 Y425 W437 T455 N473 R516
Binding residue
(residue number reindexed from 1)		Q120 A124 R131 G138 R139 K315 T317 D319 Y402 W414 T432 N450 R493
Enzymatic activity
Enzyme Commision number 2.1.1.72: site-specific DNA-methyltransferase (adenine-specific).
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008168 methyltransferase activity
GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity
Biological Process
GO:0006304 DNA modification
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7qw7, PDBe:7qw7, PDBj:7qw7
PDBsum7qw7
PubMed
UniProtP43423|MTC1_GEOSE Type II methyltransferase M.BseCI (Gene Name=bseCIM)

[Back to BioLiP]