Structure of PDB 7qv8 Chain A Binding Site BS02

Receptor Information
>7qv8 Chain A (length=208) Species: 5671 (Leishmania infantum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIIMVTTGSREVDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLP
ISQGGAEGMALYIDTEGTFRPERLVAVAARYGLDPEDVLANVACARAFNT
DHQQQLLLQASAMMAENRFALIVVDSATALYRTDYSGRNELAARQMHLGK
FLRSLHNLAEEYGVAVVVTNQVSTTRLSLRKGRGEQRIIKVYDAEAIFGI
YDDGVGDA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7qv8 Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qv8 Divergent binding mode for a protozoan BRC repeat to RAD51.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		T170 E199 D258
Binding residue
(residue number reindexed from 1)		T37 E66 D125
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:7qv8, PDBe:7qv8, PDBj:7qv8
PDBsum7qv8
PubMed35502837
UniProtA4I3C9

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