Structure of PDB 7qpc Chain A Binding Site BS02

Receptor Information
>7qpc Chain A (length=327) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGISWLDIYHVVSATVPLYVSMTLGFLSARHLKLFSPEQCAGINKFVAKF
SIPLLSFQIISENNPFKMSPKLILSDILQKFLVVVVLAMVLRFWHPTGGR
GGKLGWVITGLSISVLPNTLILGMPILSAIYGDEAASILEQIVVLQSLIW
YTILLFLFELNAARAGTMKILLKAWRKLIINPNTYATLIGIIWATLHFRL
GWNLPEMIDKSIHLLSDGGLGMAMFSLGLFMASQSSIIACGTKMAIITML
LKFVLGPALMIASAYCIRLKSTLFKVAILQAALPQGVVPFVFAKEYNLHP
EIISTGVIFGMLIALPTTLAYYFLLDL
Ligand information
Ligand IDDLP
InChIInChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1
InChIKeyFVXDQWZBHIXIEJ-LNDKUQBDSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0CCCCC\C=C/C\C=C/CCCCCCCC(=O)OC[C@H](CO[P@@](=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC
CACTVS 3.341CCCCCC=CCC=CCCCCCCCC(=O)OC[CH](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
ACDLabs 10.04O=C(OCC(OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COP([O-])(=O)OCC[N+](C)(C)C)CCCCCCC\C=C/C\C=C/CCCCC
OpenEye OEToolkits 1.5.0CCCCCC=CCC=CCCCCCCCC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCC=CCCCCC
CACTVS 3.341CCCCC/C=C\C\C=C/CCCCCCCC(=O)OC[C@H](CO[P]([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C/C=C\CCCCC
FormulaC44 H80 N O8 P
Name1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE;
DI-LINOLEOYL-3-SN-PHOSPHATIDYLCHOLINE
ChEMBL
DrugBankDB04372
ZINC
PDB chain7qpc Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qpc Structures and mechanism of the plant PIN-FORMED auxin transporter.
Resolution3.44 Å
Binding residue
(original residue number in PDB)		K48 F49 P222 I252
Binding residue
(residue number reindexed from 1)		K49 F50 P182 I212
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0010329 auxin efflux transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0009555 pollen development
GO:0009734 auxin-activated signaling pathway
GO:0010315 auxin export across the plasma membrane
GO:0055085 transmembrane transport
GO:0060918 auxin transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071944 cell periphery

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qpc, PDBe:7qpc, PDBj:7qpc
PDBsum7qpc
PubMed35768502
UniProtQ9LFP6|PIN8_ARATH Auxin efflux carrier component 8 (Gene Name=PIN8)

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