Structure of PDB 7q38 Chain A Binding Site BS02

Receptor Information
>7q38 Chain A (length=228) Species: 64091 (Halobacterium salinarum NRC-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITGRPEWIWLALGAALMGLGALYFLVKGMGVSDPDAKKFYAITALVPAIA
FTMYLSMLLGYGLTMVPFGGEQNPIYWARYADWLFTTPLLLLDLALLVDA
DQGTILALVGADGIMIGTGLVGALTKVYSYRFVWWAISTAAMLYILYVLF
FGFTSKAESMRPEVASTFKVLRNVTVVLWSAYPVVWLIGSEGAGIVPLNI
ETLLFMVLDVSAKVGFGLILLRSRAIFG
Ligand information
Ligand IDAR
InChIInChI=1S/Ar
InChIKeyXKRFYHLGVUSROY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Ar]
FormulaAr
NameARGON
ChEMBL
DrugBank
ZINC
PDB chain7q38 Chain A Residue 322 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7q38 High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		L93 L97 T178 W182 F219
Binding residue
(residue number reindexed from 1)		L90 L94 T175 W179 F216
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0009881 photoreceptor activity
GO:0015454 light-driven active monoatomic ion transmembrane transporter activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0007602 phototransduction
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7q38, PDBe:7q38, PDBj:7q38
PDBsum7q38
PubMed35422073
UniProtP02945|BACR_HALSA Bacteriorhodopsin (Gene Name=bop)

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