Structure of PDB 7p8x Chain A Binding Site BS02

Receptor Information
>7p8x Chain A (length=282) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQFDFVKDKKYNKDALIVK
MQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVSLINYLPK
NKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVD
KQNSKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDN
QLPPLVQSGFNPSFITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTG
IYAERKHNAFVNRNFVVRYEVNWKTHEIKVKG
Ligand information
Ligand IDSO4
InChIInChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
InChIKeyQAOWNCQODCNURD-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-]S(=O)(=O)[O-]
CACTVS 3.341[O-][S]([O-])(=O)=O
ACDLabs 10.04[O-]S([O-])(=O)=O
FormulaO4 S
NameSULFATE ION
ChEMBL
DrugBankDB14546
ZINC
PDB chain7p8x Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7p8x Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		K67 K249
Binding residue
(residue number reindexed from 1)		K40 K222
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051715 cytolysis in another organism
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:7p8x, PDBe:7p8x, PDBj:7p8x
PDBsum7p8x
PubMed35311641
UniProtQ2FXB0|LUKEV_STAA8 Leucotoxin LukEv (Gene Name=lukEv)

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