Structure of PDB 7p7x Chain A Binding Site BS02

Receptor Information

>7p7x Chain A (length=282) Species: 760192 (Haliscomenobacter hydrossis DSM 1100)

HMIKYYNINGQQVPVENATLHVSDLSILRGYGIFDYFLAREGHPLFLDDY
LNRFYRSAAELYLEIPFDKAELRRQIYALLQANEVREAGIRLVLTGGYSP
DGYTPVNPNLLIMMYDLPASAWEFSAQGIKIITHPFQRELPEVKTINYST
GIRMLKTIKERGATDLIYVDQGEWIRESARSNFFLVMPDNTIVTADEKIL
WGITRRQVIDAAREAGYAVEERRIHITELDQAREAFFTSTIKGVMAIGQI
DDRVFGDGTIGKVTQELQDLFVGKVKAYLETC

Ligand information

• Ligand ID: PO4
• InChI: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
• InChIKey: NBIIXXVUZAFLBC-UHFFFAOYSA-K
• SMILES:
  CACTVS 3.341: [O-][P]([O-])([O-])=O
  ACDLabs 10.04: [O-]P([O-])([O-])=O
  OpenEye OEToolkits 1.5.0: [O-]P(=O)([O-])[O-]
• Formula: O4 P
• Name: PHOSPHATE ION
• DrugBank: DB14523
• PDB chain: 7p7x Chain A Residue 302

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7p7x The Uncommon Active Site of D-Amino Acid Transaminase from Haliscomenobacter hydrossis : Biochemical and Structural Insights into the New Enzyme.
• Resolution: 2.0 Å
• Binding residue (original residue number in PDB): L46 D47 R72 Y277
• Binding residue (residue number reindexed from 1): L47 D48 R73 Y278
• Annotation score: 3

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0008483 transaminase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0019752 carboxylic acid metabolic process
• GO:0046394 carboxylic acid biosynthetic process

External links

• PDB: RCSB:7p7x, PDBe:7p7x, PDBj:7p7x
• PDBsum: 7p7x
• PubMed: 34443642
• UniProt: F4KWH0