Structure of PDB 7owz Chain A Binding Site BS02

Receptor Information
>7owz Chain A (length=380) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKLSLIKVVNGCRLGKIQNLGKAGDCTVDIPGCLLYTRTGSAPHLTHQTL
RNIHGVPGIAQLTLSSLAEHHEVLAEYKKGVGSFIGMPESLFYCSLHDPV
TPGPAGYVTSKSVSVWGFGGRVEMTVSKFMAIQEALQPDWFQCLSDGEAS
CAETTSIKRARKSVDRSLLFLDSCLRLQEESEVLQKSVIIGVIEGGDVME
ERLRSARETAKRPVGGFLLDGFQGDPAVTETRLHLLSSVTAELPEDKPRL
ICGVSRPDEVLECIERGVDLFESFFPYQVTERGCALTFTFDCEMTSFEIN
LKEKKYQEDFDPLVRGCSCYCCKNHTRAYIHHLLMTNELLAGVLLMMHNF
EHYFGFFCSIREALKNDTLAQLKELICRQM
Ligand information
Ligand IDTEW
InChIInChI=1S/O6Te.H2O.17O.6W/c1-7(2,3,4,5)6;;;;;;;;;;;;;;;;;;;;;;;;/h;1H2;;;;;;;;;;;;;;;;;;;;;;;/q;;;;;;;;;;;;;6*-1;;;;;;+1/p-1
InChIKeyJDLYBIMRCSJRQJ-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6[O-]=[W]123(O[W]45(=O)(O1[Te]6789O2[W]1(=O)(O3)(O6[W]2(=O)(O1)(O7[W]1(=O)(O2)(O8[W](=O)(O94)(O5)(O1)[O-])[O-])[O-])[O-])[O-])[O]
FormulaO24 Te W6
Name6-tungstotellurate(VI)
ChEMBL
DrugBank
ZINC
PDB chain7owz Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7owz Structural and Biochemical Investigation of the Heterodimeric Murine tRNA-Guanine Transglycosylase.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Y107 G120 R121
Binding residue
(residue number reindexed from 1)		Y107 G120 R121
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.2.29: tRNA-guanosine(34) preQ1 transglycosylase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008479 tRNA-guanosine(34) queuine transglycosylase activity
GO:0016763 pentosyltransferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0101030 tRNA-guanine transglycosylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0032473 cytoplasmic side of mitochondrial outer membrane
GO:0032991 protein-containing complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7owz, PDBe:7owz, PDBj:7owz
PDBsum7owz
PubMed35815944
UniProtB8ZXI1|QTRT2_MOUSE Queuine tRNA-ribosyltransferase accessory subunit 2 (Gene Name=Qtrt2)

[Back to BioLiP]